Technical Data

031627
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu
Accession #
NP_065433.2
Gene ID
108
Gene #
ADCY2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ADCY2, ID (ADCY2, KIAA1060, Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2)
ADCY2, KIAA1060, Adenylate cyclase type 2, ATP pyrophosphate-lyase 2, Adenylate cyclase type II, Adenylyl cyclase 2

This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ADCY2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 458-489 amino acids from the Central region of human ADCY2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Halls, M.L., et al. EMBO J. 29(16):2772-2787(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Need, A.C., et al. Eur. J. Hum. Genet. 17(7):946-957(2009)|Uhl, G.R., et al. Arch. Gen. Psychiatry 65(6):683-693(2008)|Sunahara, R.K., et al. Mol. Interv. 2(3):168-184(2002)
USBio References
No references available
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