031638
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E FC IHC WBCrossreactivity
Hu MoAccession #
NP_000661.2Gene ID
127Gene #
ADH4Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-ADH4, CT (ADH4, Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain)
ADH4, Alcohol dehydrogenase 4, Alcohol dehydrogenase class II pi chain
This gene encodes class II alcohol dehydrogenase 4 pi subunit, which is a member of the alcohol dehydrogenase family. Members of this enzyme family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. Class II alcohol dehydrogenase is a homodimer composed of 2 pi subunits. It exhibits a high activity for oxidation of long-chain aliphatic alcohols and aromatic alcohols and is less sensitive to pyrazole. This gene is localized to chromosome 4 in the cluster of alcohol dehydrogenase genes.
Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ADH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-356 amino acids from the C-terminal region of human ADH4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Pochareddy, S., et al. Gene 460 (1-2), 1-7 (2010) :|Preuss, U.W., et al. Addict Biol (2010) In press :|Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)|Rainero, I., et al. Headache 50(1):92-98(2010)|Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :USBio References
No references available