Technical Data

031694
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004495.2; NP_001128661.1; NP_001128660.1
Gene ID
3267
Gene #
AGFG1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-AGFG1, NT (AGFG1, HRB, RAB, RIP, Arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, Rev-interacting protein, Rev/Rex activation domain-binding protein)
AGFG1, HRB, RAB, RIP, Arf-GAP domain and FG repeat-containing protein 1, HIV-1 Rev-binding protein, Nucleoporin-like protein RIP, Rev-interacting protein, Rev/Rex activation domain-binding protein

The protein encoded by this gene is related to nucleoporins, a class of proteins that mediate nucleocytoplasmic transport. The encoded protein binds the activation domain of the human immunodeficiency virus Rev protein when Rev is assembled onto its RNA target, and is required for the nuclear export of Rev-directed RNAs. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AGFG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human AGFG1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bowes, J.D., et al. Pharmacogenet. Genomics 19(4):319-323(2009)|Chaineau, M., et al. J. Biol. Chem. 283(49):34365-34373(2008)|Pryor, P.R., et al. Cell 134(5):817-827(2008)|Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)|Olsen, J.V., et al. Cell 127(3):635-648(2006)
USBio References
No references available
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