Technical Data

031727
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IF WB
Crossreactivity
Hu
Gene ID
9447
Gene #
AIM2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-AIM2, NT (AIM2, Interferon-inducible protein AIM2, Absent in melanoma 2)
AIM2, Interferon-inducible protein AIM2, Absent in melanoma 2

AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2.

Applications
Suitable for use in Western Blot, Immunofluorescence, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilution
Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-1:50 Immunofluorescence: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 4-32 in the N-terminal region of human AIM2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human AIM2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Patsos, G., et al. Int. J. Cancer 126(8):1838-1849(2010) 2. Patsos, G., et al. Glycobiology 19(7):726-734(2009) 3. Fernandes-Alnemri, T., et al. Nature 458(7237):509-513(2009) 4. Hornung, V., et al. Nature 458(7237):514-518(2009) 5. Woerner, S.M., et al. Genes Chromosomes Cancer 46(12):1080-1089(2007) 5. Cresswell, K.S., et al. Biochem. Biophys. Res. Commun. 326(2):417-424(2005)
USBio References
No references available
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