Technical Data

031770-HRP
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Conjugate
HRP
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Gene ID
224
Gene #
ALDH3A2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Notes
Preservative Free
Rabbit Anti-ALDH3A2 (ALDH3A2, ALDH10, FALDH, Fatty aldehyde dehydrogenase, Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, Microsomal aldehyde dehydrogenase) (Azide free) (HRP)
ALDH3A2, ALDH10, FALDH, Fatty aldehyde dehydrogenase, Aldehyde dehydrogenase 10, Aldehyde dehydrogenase family 3 member A2, Microsomal aldehyde dehydrogenase

Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. ALDH3A2 catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome.

Applications
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested.
Recommended Dilutions
Immunohistochemistry: Formalin fixed, paraffin embedded tissues Optimal dilutions to be determined by the researcher.
Storage and Stability
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Note: Sodium azide is a potent inhibitor of peroxidase and should not be added to HRP conjugates. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Immunogen
Recombinant protein corresponding to human ALDH3A2.
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Horseradish peroxidase (HRP).
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ALDH3A2.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Chang, C., et al., Genomics 40(1):80-85 (1997). 2. Rogers, G.R., et al., Genomics 39(2):127-135 (1997). 3. De Laurenzi, V., et al., Nat. Genet. 12(1):52-57 (1996). 4. Rogers, G.R., et al., Am. J. Hum. Genet. 57(5):1123-1129 (1995). 5. Pigg, M., et al., Nat. Genet. 8(4):361-364 (1994).
USBio References
No references available
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