Technical Data

031813
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Gene ID
247
Gene #
ALOX15B
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ALOX15B, CT (ALOX15B, Arachidonate 15-lipoxygenase B, 15-lipoxygenase 2, Arachidonate 15-lipoxygenase type II)
ALOX15B, Arachidonate 15-lipoxygenase B, 15-lipoxygenase 2, Arachidonate 15-lipoxygenase type II

ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:50-100 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ALOX15B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 605~634 amino acids from the C-terminal region of human ALOX15B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Recognizes human ALOX15B

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Wecksler,A.T., et.al., Biochemistry 48 (36), 8721-8730 (2009)|Kawakami,Y., et.al, Biosci. Biotechnol. Biochem. 73 (8), 1811-1817 (2009)
USBio References
No references available
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