Technical Data

031946
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004635.2
Gene ID
8120
Gene #
AP3B2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-AP3B2, NT (AP3B2, AP-3 complex subunit beta-2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 subunit beta-2, Beta-3B-adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP)
AP3B2, AP-3 complex subunit beta-2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 subunit beta-2, Beta-3B-adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP

Adaptor protein-3 (AP3) is a heterotetrameric vesicle-coat protein complex. Some AP3 subunits are ubiquitously expressed, whereas others are expressed exclusively in neurons. The neuron-specific AP3 complex, which includes AP3B2, is thought to serve neuron-specific functions such as neurotransmitter release (Grabner et al., 2006 [PubMed 16788073]).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AP3B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human AP3B2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Nicolas, E., et al. Eur. J. Hum. Genet. 18(10):1107-1113(2010)|Hashimoto, R., et al. Neurosci. Res. 65(1):113-115(2009)|Chen, C., et al. DNA Seq. 18(3):165-168(2007)|Grabner, C.P., et al. Proc. Natl. Acad. Sci. U.S.A. 103(26):10035-10040(2006)|Dubois, T., et al. Biochem. Biophys. Res. Commun. 301(2):502-508(2003)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net