031951
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_006585.2Gene ID
10717Gene #
AP4B1Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-AP4B1, ID (AP4B1, AP-4 complex subunit beta-1, AP-4 adapter complex subunit beta, Adapter-related protein complex 4 subunit beta-1, Beta subunit of AP-4, Beta4-adaptin)
AP4B1, AP-4 complex subunit beta-1, AP-4 adapter complex subunit beta, Adapter-related protein complex 4 subunit beta-1, Beta subunit of AP-4, Beta4-adaptin
The heterotetrameric adaptor protein (AP) complexes sort integral membrane proteins at various stages of the endocytic and secretory pathways. AP4 is composed of 2 large chains, beta-4 (AP4B1) and epsilon-4 (AP4E1; MIM 607244), a medium chain, mu-4 (AP4M1; MIM 602296), and a small chain, sigma-4 (AP4S1; MIM 607243).
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
AP4B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 491-520 amino acids from the Central region of human AP4B1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :|Cayrol, C., et al. Biochem. Biophys. Res. Commun. 298(5):720-730(2002)|Takatsu, H., et al. Biochem. Biophys. Res. Commun. 284(4):1083-1089(2001)|Hirst, J., et al. Mol. Biol. Cell 10(8):2787-2802(1999)|Dell'Angelica, E.C., et al. J. Biol. Chem. 274(11):7278-7285(1999)USBio References
No references available