032039
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_001020787.2; NP_112595.2; NP_001036134.1Gene ID
83478Gene #
ARHGAP24Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-ARHGAP24, CT (ARHGAP24, FILGAP, Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, RAC1- and CDC42-specific GTPase-activating protein of 72kD, Rho-type GTPase-activating protein 24, RhoGAP of 73kD, Sarcoma antigen NY-SAR-88, p73RhoGAP)
ARHGAP24, FILGAP, Rho GTPase-activating protein 24, Filamin-A-associated RhoGAP, RAC1- and CDC42-specific GTPase-activating protein of 72kD, Rho-type GTPase-activating protein 24, RhoGAP of 73kD, Sarcoma antigen NY-SAR-88, p73RhoGAP
ARHGAPs, such as ARHGAP24, encode negative regulators of Rho GTPases (see ARHA; MIM 165390), which are implicated in actin remodeling, cell polarity, and cell migration (Katoh and Katoh, 2004 [PubMed 15254788]).
Applications
Suitable for use in Western Blot and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 587-616 in the C-terminal region of human ARHGAP24, Swiss/UniProt Accession: Q8N264
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes human ARHGAP24.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
1. Horinouchi, M., et al. Pediatr Hematol Oncol 27(5):344-354(2010) 2. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : 3. Holm, H., et al. Nat. Genet. 42(2):117-122(2010) 4. Pfeufer, A., et al. Nat. Genet. 42(2):153-159(2010) 5. Nakamura, F., et al. PLoS ONE 4 (3), E4928 (2009) :USBio References
No references available