Isoform 2 may act as a competitive inhibitor of calmodulin-dependent enzymes such as calcineurin in neurons (By similarity).
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ARPP-21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 84-114 amino acids from the N-terminal region of human ARPP-21.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)|Brill, L.M., et al. Anal. Chem. 76(10):2763-2772(2004)
USBio References
No references available
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