Technical Data

032119
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hm Hu
Accession #
NP_001137250.1; NP_060177.2
Gene ID
55616
Gene #
ASAP3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ASAP3, NT (ASAP3, DDEFL1, UPLC1, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1)
ASAP3, DDEFL1, UPLC1, Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3, Development and differentiation-enhancing factor-like 1, Protein up-regulated in liver cancer 1

This gene encodes a member of a subfamily of ADP-ribosylation factor(Arf) GTPase-activating proteins that contain additional ankyrin repeat and pleckstrin homology domains. The Arf GAP domain of this protein catalyzes the hydrolysis of GTP bound to Arf proteins. The encoded protein promotes cell differentiation and migration and has been implicated in cancer cell invasion. Alternative splicing results in multiple transcript variants.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ASAP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-54 amino acids from the N-terminal region of human ASAP3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, Hamster

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Ismail, S.A., et al. Cell 141(5):812-821(2010)|Ha, V.L., et al. J. Biol. Chem. 283(22):14915-14926(2008)|Fang, Z., et al. Mol. Cell Proteomics 5(8):1437-1449(2006)|Okabe, H., et al. Int. J. Oncol. 24(1):43-48(2004)
USBio References
No references available
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