Technical Data

032126
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_665862.1; NP_057199.1
Gene ID
51130
Gene #
ASB3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ASB3, NT (ASB3, Ankyrin repeat and SOCS box protein 3)
ASB3, Ankyrin repeat and SOCS box protein 3

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ASB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human ASB3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yang, Q., et al. BMC Med. Genet. 8 SUPPL 1, S12 (2007) : Chung, A.S., et al. Mol. Cell. Biol. 25(11):4716-4726(2005) Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002) Kile, B.T., et al. Mol. Cell. Biol. 21(18):6189-6197(2001) Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000) :
USBio References
No references available
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