Technical Data

032127
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_057200.1; NP_665879.1
Gene ID
51666
Gene #
ASB4
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ASB4, CT (ASB4, Ankyrin repeat and SOCS box protein 4)
ASB4, Ankyrin repeat and SOCS box protein 4

The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ASB4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 225-255 amino acids from the C-terminal region of human ASB4.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Li, J.Y., et al. J. Neuroendocrinol. 17(6):394-404(2005)|Kile, B.T., et al. Trends Biochem. Sci. 27(5):235-241(2002)|Kile, B.T., et al. Gene 258 (1-2), 31-41 (2000) :
USBio References
No references available
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