Technical Data

032138
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
438
Gene #
ASMT
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-ASMT, ID (ASMT, Acetylserotonin O-methyltransferase, Hydroxyindole O-methyltransferase)
ASMT, Acetylserotonin O-methyltransferase, Hydroxyindole O-methyltransferase

ASMT belongs to the methyltransferase superfamily, and is located in the pseudoautosomal region (PAR) at the end of the short arms of the X and Y chromosomes. The encoded enzyme catalyzes the final reaction in the synthesis of melatonin, and is abundant in the pineal gland.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
ASMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219~249 amino acids from the Central region of human ASMT.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Melke, J., et al. Mol. Psychiatry 13(1):90-98(2008)|Toma, C., et al. Mol. Psychiatry 12(11):977-979(2007)|Ross, M.T., et al. Nature 434(7031):325-337(2005)|Itoh, M.T., et al. Horm. Metab. Res. 35(3):153-157(2003)
USBio References
No references available
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