Technical Data

032472
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu Mo
Accession #
NP_001698.2
Gene ID
9275
Gene #
BCL7B
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-BCL7B, CT (BCL7B, B Cell CLL/lymphoma 7 protein family member B, Allergen=Hom s 3)
BCL7B, B-cell CLL/lymphoma 7 protein family member B, Allergen=Hom s 3

This gene encodes a member of the BCL7 family including BCL7A, BCL7B and BCL7C proteins. This member is BCL7B, which contains a region that is highly similar to the N-terminal segment of BCL7A or BCL7C proteins. The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line. This gene is located at a chromosomal region commonly deleted in Williams syndrome. This gene is highly conserved from C. elegans to human. Multiple alternatively spliced transcript variants have been found for this gene.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
BCL7B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 136-164 amino acids from the C-terminal region of human BCL7B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Fontaine-Bisson, B., et al. Diabetologia 53(10):2155-2162(2010)|Kathiresan, S., et al. Nat. Genet. 40(2):189-197(2008)|Willer, C.J., et al. Nat. Genet. 40(2):161-169(2008)|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Jadayel, D.M., et al. Gene 224 (1-2), 35-44 (1998) :
USBio References
No references available
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