Technical Data

032546
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Accession #
NP_033888.2
Gene ID
12166
Gene #
Bmpr1a
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-Bmpr1a, ID (Bmpr1a, Acvrlk3, Bmpr, Bone morphogenetic protein receptor type-1A, Activin receptor-like kinase 3, BMP-2/BMP-4 receptor, Serine/threonine-protein kinase receptor R5, CD292)
Bmpr1a, Acvrlk3, Bmpr, Bone morphogenetic protein receptor type-1A, Activin receptor-like kinase 3, BMP-2/BMP-4 receptor, Serine/threonine-protein kinase receptor R5, CD292

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Mouse Bmpr1a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 169-197 amino acids from the Central region of human Mouse Bmpr1a.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Drogat, B., et al. Blood 116(12):2141-2151(2010)|Leung, A.W., et al. Dev. Dyn. 239(9):2319-2329(2010)|Mira, H., et al. Cell Stem Cell 7(1):78-89(2010)|Libusova, L., et al. Development 137(14):2297-2305(2010)|Caronia, G., et al. J. Neurosci. 30(18):6291-6301(2010)
USBio References
No references available
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