Technical Data

033108
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E FC WB
Crossreactivity
Hu
Gene ID
23632
Gene #
CA14
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CA14, NT (CA14, Carbonic anhydrase 14, Carbonate dehydratase XIV, Carbonic anhydrase XIV)
CA14, Carbonic anhydrase 14, Carbonate dehydratase XIV, Carbonic anhydrase XIV

CA14 belongs a large family of zinc metalloenzymes that catalyze the versible hydration of carbon dioxide. The protein is predicted to be a type I membrane protein and shares highest sequence similarity with the other transmembrane CA isoform, CA XII; however, they have different patterns of tissue-specific expression and thus may play different physiologic roles.

Applications
Suitable for use in Western Blot, Indirect Flow Cytometry and ELISA. Other applications not tested.
Recommended Dilution
Western Blot: 1:1000 Indirect Flow Cytometry: 1:10-50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 51-80 from the N-terminal region of human CA14.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Specificity
Recognizes human CA14.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Parkkila,S. Natl. Acad. Sci. U.S.A. 98(4):1918-1923 (2001), 2. Fujikawa-Adachi, K., Nishimori,I. Genomics 61(1):74-81 (1999), 3. Tarun,A.S., Bryant,B. Chem. Senses 28(7):621-629 (2003)
USBio References
No references available
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