Technical Data

033130
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_954855.1; NP_000714.3
Gene ID
782
Gene #
CACNB1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CACNB1, CT (CACNB1, CACNLB1, Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltage-dependent subunit beta 1)
CACNB1, CACNLB1, Voltage-dependent L-type calcium channel subunit beta-1, Calcium channel voltage-dependent subunit beta 1

The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CACNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 542-572 amino acids from the C-terminal region of human CACNB1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Jangsangthong, W., et al. Pflugers Arch. 459(3):399-411(2010)|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Olsen, J.V., et al. Cell 127(3):635-648(2006)|Lim, J., et al. Cell 125(4):801-814(2006)|Foell, J.D., et al. Physiol. Genomics 17(2):183-200(2004)
USBio References
No references available
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