Technical Data

033179
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_653176.2
Gene ID
92291
Gene #
CAPN13
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CAPN13, CT (CAPN13, Calpain-13, Calcium-activated neutral proteinase 13)
CAPN13, Calpain-13, Calcium-activated neutral proteinase 13

Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN13 belongs to the calpain large subunit family.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CAPN13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 536-565 amino acids from the C-terminal region of human CAPN13.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Taylor, J.Y., et al. Biol Res Nurs 12(2):149-155(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Hillier, L.W., et al. Nature 434(7034):724-731(2005)|Dear, T.N., et al. Gene 274 (1-2), 245-252 (2001) :|Dear, T.N., et al. Genomics 68(2):152-160(2000)
USBio References
No references available
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