Technical Data

033434
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_006632.2; NP_112477.1
Gene ID
10803
Gene #
CCR9
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CCR9, CT (CCR9, GPR28, C-C chemokine receptor type 9, G-protein coupled receptor 28, GPR-9-6, CDw199)
CCR9, GPR28, C-C chemokine receptor type 9, G-protein coupled receptor 28, GPR-9-6, CDw199

The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CCR9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 305-334 amino acids from the C-terminal region of human CCR9.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Han, S., et al. Hum. Immunol. 71(7):727-730(2010)|Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010)|Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)|Segat, L., et al. Vaccine 28(10):2201-2206(2010)|Wang, Y., et al. Cell. Mol. Immunol. 7(1):51-60(2010)
USBio References
No references available
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