Technical Data

033732
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E IHC WB
Crossreactivity
Hu
Gene ID
1044
Gene #
CDX1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CDX1, CT (CDX1, Homeobox protein CDX-1, Caudal-type homeobox protein 1)
CDX1, Homeobox protein CDX-1, Caudal-type homeobox protein 1

This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CDX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 236~265 amino acids from the C-terminal region of human CDX1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Domon-Dell, C., et al., Oncogene 22(39):7913-7921 (2003).|Suh, E.R., et al., J. Biol. Chem. 277(39):35795-35800 (2002).|Mizoshita, T., et al., Gastric Cancer 4(4):185-191 (2001).|Mallo, G.V., et al., Int. J. Cancer 74(1):35-44 (1997).|Bonner, C.A., et al., Genomics 28(2):206-211 (1995).
USBio References
No references available
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