Technical Data

033866
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_660277
Gene ID
91851
Gene #
CHRDL1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CHRDL1, NT (CHRDL1, NRLN1, Chordin-like protein 1, Neuralin-1, Neurogenesin-1, Ventroptin)
CHRDL1, NRLN1, Chordin-like protein 1, Neuralin-1, Neurogenesin-1, Ventroptin

CHRDL1 is an antagonist of bone morphogenetic protein 4. The encoded protein may play a role in topographic retinotectal projection and in the regulation of retinal angiogenesis in response to hypoxia. Alternatively spliced transcript variants encoding different isoforms have been described.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CHRDL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-35 amino acids from the N-terminal region of human CHRDL1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Fernandes, H., et al. Cells Tissues Organs (Print) 191(6):443-452(2010)|Larman, B.W., et al. J. Am. Soc. Nephrol. 20(5):1020-1031(2009)|Kane, R., et al. Mol. Vis. 14, 1138-1148 (2008) :|Kosinski, C., et al. Proc. Natl. Acad. Sci. U.S.A. 104(39):15418-15423(2007)|Gazzerro, E., et al. Rev Endocr Metab Disord 7 (1-2), 51-65 (2006) :
USBio References
No references available
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