Technical Data

034052
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_056270.2
Gene ID
57472
Gene #
CNOT6
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CNOT6, CT (CNOT6, CCR4, KIAA1194, CCR4-NOT transcription complex subunit 6, CCR4 carbon catabolite repression 4-like, Carbon catabolite repressor protein 4 homolog, Cytoplasmic deadenylase)
CNOT6, CCR4, KIAA1194, CCR4-NOT transcription complex subunit 6, CCR4 carbon catabolite repression 4-like, Carbon catabolite repressor protein 4 homolog, Cytoplasmic deadenylase

The protein encoded by this gene is a subunit of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substates.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CNOT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic between 415-442 amino acids selected from the C-terminal region of human CNOT6.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Edwards, T.L., et al. Ann. Hum. Genet. 74(2):97-109(2010)|Lau, N.C., et al. Biochem. J. 422(3):443-453(2009)|Sanchez-Perez, I., et al. Cancer Lett. 273(2):281-291(2009)|Garapaty, S., et al. J. Biol. Chem. 283(11):6806-6816(2008)|Morita, M., et al. Mol. Cell. Biol. 27(13):4980-4990(2007)
USBio References
No references available
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