Technical Data

034074
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
22796
Gene #
COG2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-COG2, NT (COG2, LDLC, Conserved oligomeric Golgi complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein)
COG2, LDLC, Conserved oligomeric Golgi complex subunit 2, Component of oligomeric Golgi complex 2, Low density lipoprotein receptor defect C-complementing protein

COG2 encodes a subunit of the conserved oligomeric Golgi complex that is required for maintaining normal structure and activity of the Golgi complex. The encoded protein specifically interacts with the USO1 vesicle docking protein and may be necessary for normal Golgi ribbon formation and trafficking of Golgi enzymes.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
COG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103~132 amino acids from the N-terminal region of human COG2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Edwards, T.L., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (5), 721-735 (2009)|Luke, M.M., et al. Stroke 40(2):363-368(2009)|Shiffman, D., et al. Arterioscler. Thromb. Vasc. Biol. 28(1):173-179(2008)|Sohda, M., et al. Traffic 8(3):270-284(2007)|Ungar, D., et al. Trends Cell Biol. 16(2):113-120(2006)
USBio References
No references available
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Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net