034187
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_001138609.1; NP_001138607.1Gene ID
1375Gene #
CPT1BShipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-CPT1B, CT (CPT1B, KIAA1670, Carnitine O-palmitoyltransferase 1, muscle isoform, Carnitine O-palmitoyltransferase I, muscle isoform, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein)
CPT1B, KIAA1670, Carnitine O-palmitoyltransferase 1, muscle isoform, Carnitine O-palmitoyltransferase I, muscle isoform, Carnitine palmitoyltransferase 1B, Carnitine palmitoyltransferase I-like protein
The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-chain fatty acyl-CoAs from the cytoplasm into the mitochondria. Multiple transcript variants encoding different isoforms have been found for this gene, and read-through transcripts are expressed from the upstream locus that include exons from this gene.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CPT1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 743-771 amino acids from the C-terminal region of human CPT1B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Matsuo, T., et al. Biochem. Genet. 48 (3-4), 193-201 (2010) :|Miljkovic, I., et al. Obesity (Silver Spring) 17(7):1396-1401(2009)|Miyagawa, T., et al. PLoS ONE 4 (4), E5394 (2009) :|van der Leij, F.R., et al. J. Biol. Chem. 277(30):26994-27005(2002)|Yamazaki, N., et al. J. Biol. Chem. 275(41):31739-31746(2000)USBio References
No references available