034298
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_001121128.1; NP_003467.1Gene ID
8048Gene #
CSRP3Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-CSRP3, ID (CSRP3, CLP, MLP, Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, LIM domain protein, cardiac, Muscle LIM protein)
CSRP3, CLP, MLP, Cysteine and glycine-rich protein 3, Cardiac LIM protein, Cysteine-rich protein 3, LIM domain protein, cardiac, Muscle LIM protein
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CSRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the Central region of human CSRP3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Zimmerman, R.S., et al. Genet. Med. 12(5):268-278(2010)|Rampersaud, E., et al. Ann. Hum. Genet. 74(2):110-116(2010)|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Moller, D.V., et al. Eur. J. Heart Fail. 11(11):1031-1035(2009)USBio References
No references available