Technical Data

034435
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IF IHC WB
Crossreactivity
Hu
Accession #
NP_085125.1
Gene ID
29785
Gene #
CYP2S1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-CYP2S1, CT (CYP2S1, Cytochrome P450 2S1, CYPIIS1)
CYP2S1, Cytochrome P450 2S1, CYPIIS1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. In rodents, the homologous protein has been shown to metabolize certain carcinogens; however, the specific function of the human protein has not been determined.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Immunofluorescence 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
CYP2S1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-436 amino acids from the C-terminal region of human CYP2S1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bui, P.H., et al. Mol. Pharmacol. 76(5):1031-1043(2009) Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009) Deb, S., et al. Expert Opin Drug Metab Toxicol 5(4):367-380(2009) Jang, Y.J., et al. Ther Drug Monit 29(3):292-298(2007) Hanzawa, Y., et al. Drug Metab. Pharmacokinet. 22(2):136-140(2007)
USBio References
No references available
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