Rabbit Anti-DAZAP2, CT (DAZAP2, KIAA0058, DAZ-associated protein 2, Deleted in azoospermia-associated protein 2)
DAZAP2, KIAA0058, DAZ-associated protein 2, Deleted in azoospermia-associated protein 2
DAZAP2 encodes a proline-rich protein which interacts with the deleted in azoospermia (DAZ) and the deleted in azoospermia-like gene through the DAZ-like repeats. This protein also interacts with the transforming growth factor-beta signaling molecule SARA (Smad anchor for receptor activation), eukaryotic initiation factor 4G, and an E3 ubiquitinase that regulates its stability in splicing factor containing nuclear speckles. The encoded protein may function in various biological and pathological processes including spermatogenesis, cell signaling and transcription regulation, formation of stress granules during translation arrest, RNA splicing, and pathogenesis of multiple myeloma.
Applications
Suitable for use in Western Blot, Immunohistochemistry
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DAZAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118~147 amino acids from the C-terminal region of human DAZAP2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
