Technical Data

034483
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu Mo
Gene ID
1620
Gene #
DBC1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-DBC1, NT (DBC1, DBCCR1, FAM5A, Deleted in bladder cancer protein 1, Protein FAM5A)
DBC1, DBCCR1, FAM5A, Deleted in bladder cancer protein 1, Protein FAM5A

DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DBC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 91~120 amino acids from the N-terminal region of human DBC1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human, mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Koyama, S., et al. Biochem. Biophys. Res. Commun. 392(3):357-362(2010)|Gronbaek, K., et al. Mod. Pathol. 21(5):632-638(2008)|Louhelainen, J.P., et al. Oncogene 25(16):2409-2419(2006)|Izumi, H., et al. Hum. Mol. Genet. 14(8):997-1007(2005)|Beetz, C., et al. Oncol. Rep. 13(2):335-340(2005)|Nishiyama, H., et al. Oncogene 20(23):2956-2964(2001)
USBio References
No references available
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