Technical Data

034550
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_065147.1
Gene ID
57062
Gene #
DDX24
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-DDX24, ID (DDX24, ATP-dependent RNA helicase DDX24, DEAD box protein 24)
DDX24, ATP-dependent RNA helicase DDX24, DEAD box protein 24

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DDX24 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 505-536 amino acids from the Central region of human DDX24.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Davila, S., et al. Genes Immun. 11(3):232-238(2010)|Ma, J., et al. Virology 375(1):253-264(2008)|Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)|Matsuoka, S., et al. Science 316(5828):1160-1166(2007)|Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
USBio References
No references available
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