034661
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
NP_031361.2; NP_031363.2Gene ID
9940Gene #
DLEC1Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-DLEC1, NT (DLEC1, DLC1, Deleted in lung and esophageal cancer protein 1, Deleted in lung cancer protein 1)
DLEC1, DLC1, Deleted in lung and esophageal cancer protein 1, Deleted in lung cancer protein 1
This gene contains 37 exons, spans approximately 59-kb, and is located in the 3p22-p21.3 chromosomal segment that is commonly deleted in various carcinomas. Several alternatively spliced transcripts have been observed that contain disrupted coding regions and likely encode nonfunctional proteins. Aberrant transcription of this gene may be involved in carcinogenesis of the lung, esophagus, and kidney.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DLEC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-292 amino acids from the N-terminal region of human DLEC1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Zhang, Q., et al. J. Urol. 184(2):731-737(2010)|Zhang, Y., et al. Clin Lung Cancer 11(4):264-270(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Al Sarakbi, W., et al. Anticancer Res. 30(4):1079-1082(2010)|Canova, C., et al. Cancer Res. 69(7):2956-2965(2009)USBio References
No references available