Technical Data

034730
Clone Type
Polyclonal
Host
Rabbit
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Rt
Accession #
NP_004935.1
Gene ID
1776
Gene #
DNASE1L3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-DNASE1L3, NT (DNASE1L3, DHP2, DNAS1L3, Deoxyribonuclease gamma, DNase I homolog protein DHP2, Deoxyribonuclease I-like 3, Liver and spleen DNase)
DNASE1L3, DHP2, DNAS1L3, Deoxyribonuclease gamma, DNase I homolog protein DHP2, Deoxyribonuclease I-like 3, Liver and spleen DNase

This gene encodes a member of the DNase family. The protein hydrolyzes DNA, is not inhibited by actin, and mediates the breakdown of DNA during apoptosis. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Applications
Suitable for use in Western Blot and ELISA. Other applications not tested.
Recommended Dilutions
Western Blot: 1:2000 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 14-43 in the N-terminal region of human DNASE1L3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A and peptide affinity chromatography.
Specificity
Recognizes DNASE1L3. Species Crossreactivity: rat.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) 2. Ueki, M., et al. Clin. Chim. Acta 407 (1-2), 20-24 (2009) 3. Mizuta, R., et al. Biomed. Res. 30(3):165-170(2009) 4. Boulares, H., et al. Biochem. Biophys. Res. Commun. 341(2):653-662(2006) 5. Okamoto, M., et al. Biochem. Biophys. Res. Commun. 327(1):76-83(2005)
USBio References
No references available
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