Technical Data

034763
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_060901.2
Gene ID
55816
Gene #
DOK5
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-DOK5, NT (DOK5, C20orf180, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6)
DOK5, C20orf180, Docking protein 5, Downstream of tyrosine kinase 5, Insulin receptor substrate 6

The protein encoded by this gene is a member of the DOK family of membrane proteins, which are adapter proteins involved in signal transduction. The encoded protein interacts with phosphorylated receptor tyrosine kinases to mediate neurite outgrowth and activation of the MAP kinase pathway. In contrast to other DOK family proteins, this protein does not interact with RASGAP.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
DOK5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-49 amino acids from the N-terminal region of human DOK5.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Liu, X., et al. J Am Acad Child Adolesc Psychiatry 49(1):33-41(2010)|Tabassum, R., et al. BMC Med. Genet. 11, 35 (2010) :|Shi, L., et al. Cell. Signal. 18(11):1995-2003(2006)|Cai, D., et al. J. Biol. Chem. 278(28):25323-25330(2003)|Favre, C., et al. Genes Immun. 4(1):40-45(2003)
USBio References
No references available
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