Technical Data

035019
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_114381.1
Gene ID
7458
Gene #
EIF4H
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-EIF4H, ID (EIF4H, KIAA0038, WBSCR1, WSCR1, Eukaryotic translation initiation factor 4H, Williams-Beuren syndrome chromosomal region 1 protein)
EIF4H, KIAA0038, WBSCR1, WSCR1, Eukaryotic translation initiation factor 4H, Williams-Beuren syndrome chromosomal region 1 protein

This gene encodes one of the translation initiation factors, which functions to stimulate the initiation of protein synthesis at the level of mRNA utilization. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene generates 2 transcript variants.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
EIF4H antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 126-156 amino acids from the Central region of human EIF4H.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Feng, T., et al. Hum. Genet. 128(3):269-280(2010)|Zhu, X., et al. Genet. Epidemiol. 34(2):171-187(2010)|Mokas, S., et al. Mol. Biol. Cell 20(11):2673-2683(2009)|Marintchev, A., et al. Cell 136(3):447-460(2009)|Rozovsky, N., et al. RNA 14(10):2136-2148(2008)
USBio References
No references available
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