Rabbit Anti-Ern2, CT (Ern2, Ire2, Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, Ire1-beta, Serine/threonine-protein kinase, Endoribonuclease)
Ern2, Ire2, Serine/threonine-protein kinase/endoribonuclease IRE2, Endoplasmic reticulum-to-nucleus signaling 2, Inositol-requiring protein 2, Ire1-beta, Serine/threonine-protein kinase, Endoribonuclease
Ern2 plays a role in expression of the DDIT3 transcription factor, required for the unfolded-protein response, growth arrest and apoptosis. Has no effect on 28S ribosomal RNA cleavage, unlike the corresponding human protein.
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Mouse Ern2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 882-911 amino acids from the C-terminal region of Mouse Ern2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
