Technical Data

035339
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_068373.1
Gene ID
3995
Gene #
FADS3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-FADS3, CT (FADS3, CYB5RP, Fatty acid desaturase 3, Cytochrome b5-related protein)
FADS3, CYB5RP, Fatty acid desaturase 3, Cytochrome b5-related protein

The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members FADS1 and FADS2 at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FADS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 327-355 amino acids from the C-terminal region of human FADS3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)|Mathias, R.A., et al. J. Lipid Res. 51(9):2766-2774(2010)|Barber, M.J., et al. PLoS ONE 5 (3), E9763 (2010) :|Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)|Hicks, A.A., et al. PLoS Genet. 5 (10), E1000672 (2009) :
USBio References
No references available
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