Technical Data

035562
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001014765.1
Gene ID
93611
Gene #
FBXO44
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-FBXO44, NT (FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A, F-box only protein 44, F-box protein FBX30, F-box/G-domain protein 3)
FBXO44, FBG3, FBX30, FBX44, FBX6A, FBXO6A, F-box only protein 44, F-box protein FBX30, F-box/G-domain protein 3

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FBXO44 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human FBXO44.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Kumanomidou, T., et al. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 66 (PT 1), 95-98 (2010) :|Glenn, K.A., et al. J. Biol. Chem. 283(19):12717-12729(2008)|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)|Ilyin, G.P., et al. Gene 296 (1-2), 11-20 (2002) :
USBio References
No references available
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