Technical Data

035611
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001077005.1
Gene ID
89846
Gene #
FGD3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-FGD3, CT (FGD3, ZFYVE5, FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5)
FGD3, ZFYVE5, FYVE, RhoGEF and PH domain-containing protein 3, Zinc finger FYVE domain-containing protein 5

FGD3 promotes the formation of filopodia. May activate CDC42, a member of the Ras-like family of Rho-and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape (By similarity).

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FGD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 574-601 amino acids from the C-terminal region of human FGD3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Delague, V., et al. Am. J. Hum. Genet. 81(1):1-16(2007)|Humphray, S.J., et al. Nature 429(6990):369-374(2004)|Rabizadeh, S., et al. Cytokine Growth Factor Rev. 14 (3-4), 225-239 (2003) :|Salehi, A.H., et al. J. Biol. Chem. 277(50):48043-48050(2002)
USBio References
No references available
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