Technical Data

035732
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_036318.1
Gene ID
2301
Gene #
FOXE3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-FOXE3, ID (FOXE3, FKHL12, FREAC8, Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8)
FOXE3, FKHL12, FREAC8, Forkhead box protein E3, Forkhead-related protein FKHL12, Forkhead-related transcription factor 8

This intronless gene belongs to the forkhead family of transcription factors, which is characterized by a distinct forkhead domain. The protein encoded functions as a lens-specific transcription factor and plays an important role in vertebrate lens formation. Mutations in this gene are associated with anterior segment mesenchymal dysgenesis and congenital primary aphakia.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FOXE3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the Central region of human FOXE3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Reis, L.M., et al. Am. J. Med. Genet. A 152A (3), 582-590 (2010) :|Bremond-Gignac, D., et al. Mol. Vis. 16, 1705-1711 (2010) :|Ali, M., et al. Mol. Vis. 16, 1162-1168 (2010) :|Anjum, I., et al. Mol. Vis. 16, 549-555 (2010) :|Iseri, S.U., et al. Hum. Mutat. 30(10):1378-1386(2009)
USBio References
No references available
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