035746
Clone Type
PolyclonalHost
RabbitSource
HumanIsotype
IgGGrade
Affinity PurifiedApplications
E WBCrossreactivity
HuAccession #
O00409; NP_005188.2Gene ID
1112Gene #
FOXN3Shipping Temp
Blue IceStorage Temp
-20°CRabbit Anti-FOXN3, CT (FOXN3, C14orf116, CHES1, Forkhead box protein N3, Checkpoint suppressor 1)
FOXN3, C14orf116, CHES1, Forkhead box protein N3, Checkpoint suppressor 1
This gene is a member of the forkhead/winged helix transcription factor family. Checkpoints are eukaryotic DNA damage-inducible cell cycle arrests at G1 and G2. Checkpoint suppressor 1 suppresses multiple yeast checkpoint mutations including mec1, rad9, rad53 and dun1 by activating a MEC1-independent checkpoint pathway. Alternative splicing is observed at the locus, resulting in distinct isoforms. [provided by RefSeq].
Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FOXN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 379-408 amino acids from the C-terminal region of human FOXN3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.
References
Samaan, G., et al. Biochem. Biophys. Res. Commun. 400(1):60-65(2010)|Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :|Markowski, J., et al. Eur Arch Otorhinolaryngol 266(10):1501-1507(2009)|Schlade-Bartusiak, K., et al. Am. J. Med. Genet. A 146A (1), 117-123 (2008) :USBio References
No references available