Technical Data

035767
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_004468.1
Gene ID
2483
Gene #
FRG1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-FRG1, CT (FRG1, Protein FRG1, FSHD region gene 1 protein)
FRG1, Protein FRG1, FSHD region gene 1 protein

This gene maps to a location 100 kb centromeric of the repeat units on chromosome 4q35 which are deleted in facioscapulohumeral muscular dystrophy (FSHD). It is evolutionarily conserved and has related sequences on multiple human chromosomes but DNA sequence analysis did not reveal any homology to known genes. In vivo studies demonstrate the encoded protein is localized to the nucleolus.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
FRG1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 229-257 amino acids from the C-terminal region of human FRG1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Hanel, M.L., et al. Dev. Dyn. 238(6):1502-1512(2009)|Bodega, B., et al. BMC Biol. 7, 41 (2009) :|Pirozhkova, I., et al. PLoS ONE 3 (10), E3389 (2008) :|Lamesch, P., et al. Genomics 89(3):307-315(2007)|Gabellini, D., et al. Nature 439(7079):973-977(2006)
USBio References
No references available
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