Technical Data

035854
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Gene ID
2555
Gene #
GABRA2
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GABRA2, CT (GABRA2, Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2)
GABRA2, Gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2

GABRA2 is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Indirect Flow Cytometry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GABRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384~414 amino acids from the C-terminal region of human GABRA2.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Das,S., et.al., Stat Med 29 (11), 1250-1258 (2010)|Bierut,L.J., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (11), 5082-5087 (2010)|Dixon,C.I., et.al., Proc. Natl. Acad. Sci. U.S.A. 107 (5), 2289-2294 (2010)
USBio References
No references available
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