GABRA4, ID (GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4) (PE)

035855-PE

Clone Type

Polyclonal

Host

Rabbit

Source

Human

Conjugate

Isotype

IgG

Grade

Affinity Purified

Applications

FLISA WB

Crossreactivity

Accession #

NP_000800.2

Gene ID

2557

Gene #

GABRA4

Shipping Temp

Blue Ice

Storage Temp

4°C Do Not Freeze

Notes

Preservative Free

Rabbit Anti-GABRA4, ID (GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4) (PE)

GABRA4, Gamma-aminobutyric acid receptor subunit alpha-4, GABA(A) receptor subunit alpha-4

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Applications Suitable for use in FLISA and Western Blot. Other potential application, though not tested is Direct Flow Cytometry. Other applications not tested.

Recommended Dilutions

Optimal dilutions to be determined by the researcher.

Storage and Stability

Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Immunogen

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 333-361 in the central region of human GABRA4.

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

Purity

Purified by Protein A and peptide affinity chromatography.

Specificity

Recognizes human GABRA4.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References

1. Bailey, S.D., et al. Diabetes Care (2010). 2. Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010). 3. Pinheiro, A.P., et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010). 4. Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009). 5. Tabakoff, B., et al. BMC Biol. 7, 70 (2009)

USBio References

No references available

Technical Data