Technical Data

035874
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_001463.1
Gene ID
2574
Gene #
GAGE2B
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GAGE2B, NT (GAGE2B, GAGE2, G antigen 2B/2C, Cancer/testis antigen 4.2, G antigen 2C)
GAGE2B, GAGE2, G antigen 2B/2C, Cancer/testis antigen 4.2, G antigen 2C

This gene belongs to a family of genes that are expressed in a variety of tumors but not in normal tissues, except for the testis. The sequences of the family members are highly related but differ by scattered nucleotide substitutions. The antigenic peptide YRPRPRRY, which is also encoded by several other family members, is recognized by autologous cytolytic T lymphocytes. [provided by RefSeq].

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GAGE2B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human GAGE2B.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Sun, F., et al. Mol. Cancer Ther. 8(12):3191-3202(2009)|Gjerstorff, M.F., et al. Tissue Antigens 71(3):187-192(2008)|Ross, M.T., et al. Nature 434(7031):325-337(2005)|De Backer, O., et al. Cancer Res. 59(13):3157-3165(1999)|Scarcella, D.L., et al. Clin. Cancer Res. 5(2):335-341(1999)
USBio References
No references available
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