Technical Data

035910
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_937784.2
Gene ID
2595
Gene #
GANC
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GANC, NT (GANC, Neutral alpha-glucosidase C)
GANC, Neutral alpha-glucosidase C

Glycosyl hydrolase enzymes hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. This gene encodes a member of glycosyl hydrolases family 31. This enzyme hydrolyses terminal, non-reducing 1,4-linked alpha-D-glucose residues and releases alpha-D-glucose. This is a key enzyme in glycogen metabolism and its gene localizes to a chromosomal region (15q15) that is associated with susceptibility to diabetes.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GANC antibody is generated from rabbits immunized with a KLH conjugated synthetic between 1-30 amino acids selected from the N-terminal region of human GANC.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Oba-Shinjo, S.M., et al. J. Neurol. 256(11):1881-1890(2009)|Kawabata, Y., et al. FEBS Lett. 555(3):623-630(2003)|Dgany, O., et al. Am. J. Hum. Genet. 71(6):1467-1474(2002)|Hirschhorn, R., et al. Proc. Natl. Acad. Sci. U.S.A. 99(21):13642-13646(2002)|Usuki, F., et al. Muscle Nerve 11(4):365-371(1988)
USBio References
No references available
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