Technical Data

036027
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E IHC WB
Crossreactivity
Hu
Accession #
NP_821158.2
Gene ID
2686
Gene #
GGT7
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GGT7, NT (GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 light chain)
GGT7, GGTL3, GGTL5, Gamma-glutamyltransferase 7, Gamma-glutamyltransferase-like 3, Gamma-glutamyltransferase-like 5, Gamma-glutamyltranspeptidase 7, Glutathione hydrolase 7, Gamma-glutamyltransferase 7 heavy chain, Gamma-glutamyltransferase 7 light chain

This gene is a member of a gene family that encodes enzymes involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene consists of a heavy and a light chain, and it can interact with CT120, a plasma membrane-associated protein that is possibly involved in lung carcinogenesis.

Applications
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GGT7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-53 amino acids from the N-terminal region of human GGT7.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rose, J. Phd, et al. Mol. Med. (2010) In press :|Heisterkamp, N., et al. Hum. Genet. 123(4):321-332(2008)|He, X., et al. Biochem. Biophys. Res. Commun. 297(3):528-536(2002)|Figlewicz, D.A., et al. Genomics 17(2):299-305(1993)
USBio References
No references available
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