Technical Data

036056
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_853516.1
Gene ID
349149
Gene #
GJC3
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GJC3, CT (GJC3, GJE1, Gap junction gamma-3 protein, Connexin-30.2, Connexin-31.3, Gap junction epsilon-1 protein)
GJC3, GJE1, Gap junction gamma-3 protein, Connexin-30.2, Connexin-31.3, Gap junction epsilon-1 protein

This gene encodes a gap junction protein. The encoded protein, also known as a connexin, plays a role in formation of gap junctions, which provide direct connections between neighboring cells. Mutations in this gene have been reported to be associated with nonsyndromic hearing loss.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GJC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 251-278 amino acids from the C-terminal region of human GJC3.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Yang, J.J., et al. Hum. Genet. 128(3):303-313(2010)|Ramchander, P.V., et al. Genet Test Mol Biomarkers 14(4):539-541(2010)|Hong, H.M., et al. Hum. Genet. 127(2):191-199(2010)|Wang, W.H., et al. Audiol. Neurootol. 15(2):81-87(2010)|Sargiannidou, I., et al. Neurobiol. Dis. 30(2):221-233(2008)
USBio References
No references available
United States Biological | 4 Technology Way | Salem, MA 01970
Phone 800-520-3011 | Fax 978-594-8052 | Website www.usbio.net