Technical Data

036066
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Hu
Accession #
NP_000395.2; NP_001073279.1
Gene ID
2720
Gene #
GLB1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GLB1, NT (GLB1, ELNR1, Beta-galactosidase, Acid beta-galactosidase, Elastin receptor 1)
GLB1, ELNR1, Beta-galactosidase, Acid beta-galactosidase, Elastin receptor 1

This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GLB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-109 amino acids from the N-terminal region of human GLB1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Human

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :|Dubois, P.C., et al. Nat. Genet. 42(4):295-302(2010)|Antonicelli, F., et al. Wound Repair Regen 17(5):631-638(2009)|Hofer, D., et al. Hum. Mutat. 30(8):1214-1221(2009)|Mayer, F.Q., et al. Mol. Genet. Metab. 96 (3), 148 (2009) :
USBio References
No references available
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