Technical Data

036195
Clone Type
Polyclonal
Host
Rabbit
Source
Human
Isotype
IgG
Grade
Purified
Applications
E FC IHC WB
Crossreactivity
Hu
Accession #
NP_005699.1
Gene ID
10082
Gene #
GPC6
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GPC6, CT (GPC6, Glypican-6, Secreted glypican-6)
GPC6, Glypican-6, Secreted glypican-6

The glypicans comprise a family of glycosylphosphatidylinositol- anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases.

Applications
Suitable for use in Western Blot, Immunohistochemistry, Indirect Flow Cytometry and ELISA. Other applications have not been tested.
Recommended Dilutions
Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:50-1:100 Indirect Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 496-528 in the C-terminal region of human GPC6.
Form
upplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human GPC6.

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
1. Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010). 2. Lau, C.S., et al. Br J Ophthalmol 94(3):357-362(2010). 3. Calboli, F.C., et al. PLoS ONE 5 (7), E11504 (2010). 4. Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009). 5. Campos-Xavier, A.B., et al. Am. J. Hum. Genet. 84(6):760-770(2009)
USBio References
No references available
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