Technical Data

036324
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Isotype
IgG
Grade
Affinity Purified
Applications
E WB
Crossreactivity
Mo
Accession #
NP_001073945.1;
Gene ID
389207
Gene #
GRXCR1
Shipping Temp
Blue Ice
Storage Temp
-20°C
Rabbit Anti-GRXCR1, ID (GRXCR1, DFNB25, Glutaredoxin domain-containing cysteine-rich protein 1)
GRXCR1, DFNB25, Glutaredoxin domain-containing cysteine-rich protein 1

This gene is one of 60 loci associated with autosomal-recessive nonsyndromic hearing impairment. This gene encodes a protein which contains GRX-like domains; these domains play a role in the S-glutathionylation of proteins and may be involved in actin organization in hair cells.

Applications
Suitable for use in Western Blot, ELISA
Recommended Dilution
ELISA: 1:1,000 Western Blot: 1:100-500
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
GRXCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-120 amino acids from the Central region of human GRXCR1.
Form
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity
Purified by Protein A affinity chromatography.
Specificity
Mouse

Intended for research use only. Not for use in human, therapeutic, or diagnostic applications.

References
Schraders, M., et al. Am. J. Hum. Genet. 86(2):138-147(2010)|Hillier, L.W., et al. Nature 434(7034):724-731(2005)|Harrington, J.J., et al. Nat. Biotechnol. 19(5):440-445(2001)
USBio References
No references available
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